Check out Paper Mario Bros the Stop Motion Animation. The animation was created for an Art and Alternative Media class at Boston College by a user called Smartkid82504 on Youtube and comprises of over 300 frames.
It was made from paper, coloured pencils, glue and cardboard. Graph paper was used to represent the pixels at a ratio of 1:1 and then each sprite carefully put together and moved a frame at a time.
Total time to build the stop motion animation was about 36 hours as the colouring, cutting and capture took a number of hours away. The impressive video can be seen below.